منابع مشابه
Recent Advances in Hemophilia Gene Therapy
Heterogeneous loss of function mutations at F8 and F9 genes causes X-linked recessive bleeding disorders, hemophilia A (HA) and hemophilia B (HB), respectively. HA is clinically indistinguishable from HB and accounts for more than 80% of hemophilia cases; the former affects 1/5000 and the latter 1/25000 male births worldwide. In Iran, it is estimated that around 4300 HA and 900 HB patients are ...
متن کاملRECENT ADVANCES Recent advances in cystic fibrosis
The median life expectancy for cystic fibrosis is now over 30 years, and it is projected that in newborn infants it will become more than 40 years. The identification of the cystic fibrosis gene and its product, cystic fibrosis transmembrane conductance regulator (CFTR), has widened the spectrum of the disease from the classical case of the infant with cystic fibrosis to the elderly childless m...
متن کاملRECENT ADVANCES Hepatitis C-Z: recent advances
HEPATITIS C Hepatitis C (HCV) is a flavivirus which was cloned in 1989, when it was identified as the major cause of post-transfusion hepatitis in adults and children. It is an RNA virus with a high degree of heterogeneity, which results in the rapid accumulation of mutations so that many variants may coexist in a single patient. This genetic diversity allows the virus to avoid immune surveilla...
متن کاملRecent Advances In Treatment of Acute Organophosphorous Nerve Agents Poisoning
Organophosphorous (OP) chemical warfare nerve agents mainly sarin and tabun were used during the Iran-Iraq war with high mortalities. In addition to atropine and oximes, the followings have recently been used successfully for the treatment of OP poisoning. 1. Sodium Bicarbonate: Infusion of high doses of sodium bicarbonate (5 mEq/kg in 60 min. followed by 5-6 mEq/kg/day to obtain arterial blood...
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ژورنال
عنوان ژورنال: BMJ
سال: 2001
ISSN: 0959-8138
DOI: 10.1136/bmj.322.7291.902